Effects of Nerve Growth Factor on Acetylcholinesterase Activity of Injured Spinal Cord
نویسندگان
چکیده
105 Abstract: Fourteen rats were examined and divided into two groups of 7: the control (Group a) and NGF-treated animals (Group B). All animals received a 50 g clipcompression injury to tthe spinal cord at the T9 level. In the NGF-treated animals, NGF (0.1 mg/kg NGF) was injected subcutaneously for seven days. After spinal cord injury, the mean AChE activity was 41.47±1.7122 activated substrate min/ml/gr. wet tissue and 47.52±1.471 in NGF-treated animals. The difference between Groups A and B was statistically significant (p<0.01). These results suggest the possible role of NGF in the cholinergic system.
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